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EXCEL Spreadsheets to calculate intrinsic exchange rate of amide protons
 
 
H in D2O .zip (pc) 
D in H2O .zip (pc) 
H in H2O .zip (pc) 
T in H2O .zip (pc) 
 

Based on :

  1. Yawen Bai, John S. Milne, Leland Mayne, and S. Walter Englander (1993). Primary structure effects on peptide group hydrogen exchange. Proteins: Structure, Function, and Genetics 17, 75-86.
  2. Gregory P. Connelly, Yawen Bai, Mei-Fen Jeng, and S. Walter Englander (1993). Isotope effects in peptide group hydrogen exchange. Proteins: Structure, Function, and Genetics 17, 87-92.
ExMS software for analyzing HX mass spec data

Instructions
Program Files
Tutorial and Sample Data nearly 1GB! For newer GUI versions of both ExMS and HDsite
Tutorial and Sample Data nearly 1GB! For older comand line version

Described in :

Zhong-Yuan Kan, Leland Mayne, Palaniappan Sevugan Chetty, and S. Walter Englander (2011). ExMS: Data Analysis for HX-MS Experiments. JASMS 22


HDsite software for residue resolution analysis of HX mass spec data

Instructions
Program Files

Described in :

Kan ZY, Walters BT, Mayne L, & Englander SW (2013) Protein hydrogen exchange at residue resolution by proteolytic fragmentation mass spectrometry analysis. Proc Natl Acad Sci USA 110:16438-16443.


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